Camilla Luddington, known to fans as Dr. Jo Wilson on “Grey’s Anatomy,” has shared a candid update about her health after being diagnosed with Hashimoto’s disease earlier this year.
At the 2025 Inspiration Awards in Los Angeles, she revealed to PEOPLE key changes she’s experienced since starting treatment.
“It’s still new to me,” Luddington said. “I got the diagnosis at the beginning of summer, so I’m fresh into this journey. I am on Levothyroxine, which is a thyroid medicine, and I can tell you that a lot of things have changed.”
Luddington Is Practicing Self-Care
The 41-year-old actress explained that before the diagnosis, she’d been struggling with intense fatigue, inflammation, and mental fog—symptoms she couldn’t fully explain.
Since beginning a regimen of levothyroxine, she says she’s noticed meaningful improvement: less puffiness, better energy, and the return to workouts like Barry’s Bootcamp.
“I feel like I have so much less inflammation,” she told the outlet. “I was very puffy all the time, not knowing why I was exhausted.”
She also described embracing new self-care routines, including avoiding gluten and paying close attention to how she feels day to day.
Luddington emphasized how the diagnosis brought clarity after months of confusion.
“One thing that I couldn’t understand was I had a lot of brain fog, and now I understand that when your thyroid is sort of all over the place, that’s what that can feel like,” Luddington told the outlet. “The exhaustion of brain fog. So just literally being able to be present with whoever on set, with my family, is a huge difference.”
How Luddington First Shared the Diagnosis
Camilla first announced her Hashimoto’s diagnosis in an episode of her “Call It What It Is” podcast, co-hosted with Jessica Capshaw, in early August 2025.
On the show, she spoke openly about how she’d long joked about feeling “slothy”—slow, tired, and ready for nap time—and how she initially attributed those symptoms to aging or perimenopause.
She shared that routine bloodwork she’d been putting off revealed abnormalities that pointed to an autoimmune thyroid condition.
Her doctor told her that “everything looks great except this one little thing,” and the words “autoimmune disease” stunned her at first.
Though shocked, Luddington said she soon felt relief — relief at having an explanation and relief that she could begin to manage it.
She acknowledged her health anxiety, admitting she sometimes wondered whether she was “gaslighting” herself.
But with this diagnosis in hand, she’s now focused on monitoring her treatment and sharing honestly with fans who may be on a similar path.
Hashimoto’s disease is described as an “autoimmune disorder affecting the thyroid gland,” according to the Mayo Clinic.
